Shuren Ma Selected Research

Desmosine

1/2021	A 28-day clinical trial of aerosolized hyaluronan in alpha-1 antiprotease deficiency COPD using desmosine as a surrogate marker for drug efficacy.
4/2019	Cystic fibrosis disease severity correlates with plasma levels of desmosine and isodesmosine, biomarkers of elastin degradation.
12/2018	Free Desmosine is a Sensitive Marker of Smoke-Induced Emphysema.
7/2017	Desmosine and Isodesmosine as a Novel Biomarker for Pulmonary Arterial Hypertension: A Pilot Study.
1/2017	The Pattern of Elastic Fiber Breakdown in Bleomycin-Induced Pulmonary Fibrosis May Reflect Microarchitectural Changes.
1/2017	A pilot clinical trial to determine the safety and efficacy of aerosolized hyaluronan as a treatment for COPD.
6/2015	The Ratio of Free to Bound Desmosine and Isodesmosine May Reflect Emphysematous Changes in COPD.
10/2011	The effect of secondhand smoke exposure on markers of elastin degradation.
9/2011	Matrix elastin: a promising biomarker for chronic obstructive pulmonary disease.
5/2007	Measurements of desmosine and isodesmosine by mass spectrometry in COPD.

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Shuren Ma Research Topics

Disease

15	Chronic Obstructive Pulmonary Disease (COPD) 07/2022 - 10/2003
7	Pulmonary Emphysema 01/2021 - 05/2005
6	Emphysema 12/2018 - 01/2006
4	Hemorrhage 01/2022 - 01/2017
4	Lung Diseases (Lung Disease) 01/2019 - 01/2006
3	Lung Injury 12/2018 - 11/2005
2	Disease Progression 04/2019 - 01/2018
2	Atrial Fibrillation 01/2017 - 11/2016
2	Pneumonia (Pneumonitis) 01/2007 - 11/2005
1	Ulcer 01/2022
1	Liver Diseases (Liver Disease) 05/2019
1	Cystic Fibrosis (Mucoviscidosis) 04/2019
1	Cachexia 01/2019
1	Inflammation (Inflammations) 01/2019
1	Acute Coronary Syndrome 01/2019
1	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2017
1	Pulmonary Arterial Hypertension 07/2017
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2017
1	Stroke (Strokes) 11/2016
1	Insulin Resistance 10/2016
1	Hyperlipidemias (Hyperlipidemia) 10/2016
1	Body Weight (Weight, Body) 10/2016
1	Obesity 10/2016
1	Hepatocellular Carcinoma (Hepatoma) 06/2015
1	Type 2 Diabetes Mellitus (MODY) 07/2014
1	Coronary Disease (Coronary Heart Disease) 07/2014
1	Bronchitis 10/2011
1	Coronary Artery Disease (Coronary Atherosclerosis) 10/2011
1	Asthma (Bronchial Asthma) 10/2011
1	Hyperoxia 01/2006

Drug/Important Bio-Agent (IBA)

15	ElastinIBA 07/2022 - 05/2007
10	Biomarkers (Surrogate Marker)IBA 01/2021 - 09/2011
10	DesmosineIBA 01/2021 - 05/2007
10	IsodesmosineIBA 01/2021 - 05/2007
5	Hyaluronic Acid (Hyaluronan)IBA 01/2021 - 05/2005
4	SmokeIBA 12/2018 - 05/2005
4	Pancreatic Elastase (Elastase)IBA 01/2018 - 01/2006
3	Proteins (Proteins, Gene)FDA Link 01/2019 - 08/2013
3	Peptides (Polypeptides)IBA 01/2017 - 10/2003
2	2'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA 01/2022 - 01/2017
2	Protease Inhibitors (Protease Inhibitor)IBA 01/2021 - 01/2018
2	Pharmaceutical PreparationsIBA 01/2021 - 01/2016
2	Peptide Hydrolases (Proteases)FDA Link 01/2019 - 01/2018
2	EnzymesIBA 06/2015 - 06/2015
2	Tobacco Smoke Pollution (Passive Smoking)IBA 10/2011 - 01/2007
2	EndotoxinsIBA 01/2007 - 11/2005
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2022
1	Capsules (Microcapsules)IBA 01/2022
1	Clopidogrel (Plavix)FDA Link 01/2022
1	4-hydroxy-2-nonenal (4-hydroxynonenal)IBA 05/2019
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2019
1	TicagrelorIBA 01/2019
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019
1	CytokinesIBA 01/2019
1	Janus KinasesIBA 01/2019
1	AerosolsIBA 01/2018
1	Indicators and Reagents (Reagents)IBA 01/2018
1	Glyoxal (Ethanedial)IBA 10/2017
1	Advanced Glycation End ProductsIBA 10/2017
1	Bleomycin (Blenoxane)FDA LinkGeneric 01/2017
1	indium-bleomycinIBA 01/2017
1	RivaroxabanIBA 01/2017
1	Heparin (Liquaemin)FDA LinkGeneric 01/2017
1	AnticoagulantsIBA 01/2017
1	bivalirudin (Angiomax)FDA Link 01/2017
1	Vitamin K FDA Link 01/2017
1	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 01/2017
1	Glucose (Dextrose)FDA LinkGeneric 10/2016
1	LipidsIBA 10/2016
1	jatrorrhizineIBA 10/2016
1	Fibrinogen (Factor I)FDA Link 01/2016
1	Leukocyte Elastase (Neutrophil Elastase)IBA 01/2016
1	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 07/2014
1	Amino Acids FDA Link 10/2011
1	thiamine triphosphorate (TTP)IBA 02/2009
1	Tiotropium Bromide (Spiriva)FDA Link 02/2009
1	Oxidants (Oxidizing Agents)IBA 01/2006

Therapy/Procedure

10	Therapeutics 01/2022 - 05/2007
2	Percutaneous Coronary Intervention 01/2022 - 01/2017
1	Contraindications 11/2016